It happens every autumn – the days grow cooler and shorter, Halloween decorations appear in shop windows, and someone always asks this question: “What is your advice on getting a flu shot?”

This year, that question came from an HSI member named Karen. And my answer to Karen, and to everyone who asks that question, is that I’m not in a position to give advice about flu shots. Only a doctor or other qualified health care provider should offer such advice. So while I’m not going to recommend or discourage you from a yearly flu shot, I do have information you can use to weigh the pros and cons of the vaccine, along with some useful insights about how to help your immune system prepare for the seasonal attack of virus and bacteria.

No extra charge for the antifreeze
There is no doubt that many thousands of the people who receive flu shots this season will make it from Labor Day to Memorial Day without coming down with a case of influenza. So taken at face value: if it works, it works – enough said. But you should stop reading now if you’d like to remain unaware of the complete contents of a flu shot. I’ll tell you this: it’s not pretty.

Each year the flu vaccine is newly redesigned, using several strains from different types of flu that were common the season before. So basically you’re getting a vaccine that is, in theory, ideal for protecting you from last year’s primary flu types. Meanwhile, vaccine developers cross their fingers and hope that whatever new flu mutation comes our way this season is not much different than last year’s flu.

But that shot at your doctor’s office contains much more than just flu strains. The vaccine is prepared with chicken embryo fluid, inoculated with the living flu strains. The fluid is then treated with formaldehyde to inactivate the virus. Thimerosal, a mercury derivative, is injected to help preserve the mixture. Ethylene glycol (better known as antifreeze) and another chemical called phenol are added to disinfect. And because animal cells are used for this process, animal viruses are sometimes introduced into the vaccine, undetected. This has happened as recently as 1995.

Now ask yourself: If you were intending to purchase a dietary supplement, and the label offered this warning: “May contain traces of formaldehyde, thimerosal, phenol, ethylene glycol, and animal cells,” would you buy it?

A “shot” of antioxidant
If you pick up a flu virus, you won’t necessarily come down with the flu. Whether or not you become ill will depend on how well your immune system deals with the virus. So you might say that a virus doesn’t give you the flu – an immune system that doesn’t defeat the virus is what gives you the flu. The key is immunity.

In 1999 HSI sent out a Members Alert titled “Super-immunity Against Mutating Flu Bugs.” In that Alert we told you about N-acetylcysteine (NAC) – an amino acid that naturally stimulates your body to produce glutathione, a powerful antioxidant enzyme.

Previous studies have shown that patients with ailments associated with a breakdown in the immune system are often deficient in their levels of glutathione.

NAC has been used for many years to treat chronic respiratory ailments with its ability to break up and dissolve the mucus that contributes to pneumonia, bronchitis, asthma, and sinusitis. And just a few years ago, an Italian study found that supplementation with N-acetylcysteine (NAC) significantly increased immunity to flu infection. Over a six-month trial, only 29% of those taking NAC developed symptoms of the flu, vs. 51% of those taking a placebo. Of the 262 people taking part in this study, three-quarters were over the age of 65.

As I told you in an e-Alert earlier this month (“Storm of the Eye” 10/9/02), 300 mg of NAC per day is probably both effective and safe for most people. But it’s always a good idea to consult a trusted health care provider before beginning any new supplement regimen.

Wolf on the run
In addition to NAC supplements, there are a number of other supplements that may help keep the flu away from the door. Vitamin C, vitamin E, and beta-carotene have all been shown to help fight colds and flu. And for several years HSI members have known about the advantages of selenium – a naturally occurring mineral with antioxidant properties. In an e-Alert I sent you last year (“Popular Supplement Now Shown to Stop Deadly Epidemics” 6/22/01) I told you about a study that concluded that selenium may stop viruses from mutating and becoming more potent.

And finally, we have Echinacea – the herb that’s become so well known in recent years for its apparent ability to help reduce the length and severity of colds and flu. How this is done is not yet known, although some studies have indicated that Echinacea may stimulate the production of white blood cells that are necessary to effectively manage viruses. Just last week I found a new study on Echinacea from the Southwest College of Naturopathic Medicine in Tempe, Arizona. Purported to be one of the first human studies of this herb, the researchers concluded that the effectiveness of Echinacea may lie in its ability to strengthen a specific part of the immune system that is known to attack viruses.

So if the idea of getting a flu shot is reassuring to you, don’t let me stop you. But there’s a very good chance that all the flu protection you need can be achieved by getting the right amount of sleep, eating a balanced diet, maintaining a light to moderate exercise regimen, and supplementing with a few proven helpers in the yearly fight between us and the flu bug.

…and another thing
In an e-alert I sent you last week (“Live Wires” 10/21/02) I told you about how the antioxidant coenzyme Q10 (CoQ10) appears to slow the progressive deterioration of function for patients in the early stages of Parkinson’s disease.

I received several e-mails about that one, and all of them zeroed in on one slightly confusing paragraph. Here’s a comment, for instance, from HSI member G.G.R. who said:

“One of the paragraphs in this letter either makes no sense or I don’t understand it correctly. The paragraph in question states that people receiving 1200 mg of COQ-10 showed a 40% decline in mental activity! Please explain! If that is true, then it would be dangerous to take this supplement!”

I’ll admit that I grappled with the wording of that paragraph in question, but even so, it still ended up being confusing. In describing the study results from research at the University of California, San Diego, here’s what I wrote:

“Using a scale that measures the severity of Parkinson’s symptoms, the researchers found that the 23 subjects who received the 1,200 mg dose showed a decline in mental function and muscle movement that was about 40% less than the placebo group. Subjects who received the lower dosages also showed less decline, but it was not as significant as in the high dosage group.”

It’s a double-negative problem. What I intended to say here was that all of the study groups showed a decline in mental function, but the group that received the 1,200 mg daily dose of CoQ10 experienced 40% less decline than the placebo group. So just as “less is more,” in this case “less decline” is better.

In his e-mail, G.G.R. also had this question: “Did you hear that an Italian doctor actually cures Parkinson’s with two high dosage injections of L-Glutathione. Would like to hear something about it from you.”

I have heard about this intravenous treatment. My understanding, however, is that it falls far short of being a “cure.” Apparently the large IV dose of L-Glutathione provides a dramatic relief from the severe tremors of Parkinson’s. But the effect wears off after a few days and must be repeated. To be honest, I’m not aware of any other factors that might come into play. For instance: Are there a limited number of treatments that a Parkinson’s patient can tolerate? Are the treatments exorbitantly expensive? Do you have to go to Italy to receive them?

If anyone has further information about this treatment and can provide the answers to these questions, G.G.R. and I would very much like to hear from you.

To Your Good Health…

Written by Jenny Thompson for Health Sciences Institute, and published on DrKelley.info, November 3, 2002. Embedded links (if any) may no longer be active. (Ed. 12.31.10)

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